Free access to National Equine Forum live stream

The National Equine Forum (NEF) will be open to everyone this year through a free live stream. This annual event takes place on Thursday, 6th March 2025, at the Institution of Mechanical Engineers (IMechE) in London. A limited number of in-person tickets remain available, including discounted afternoon tickets for those in equestrian education.

“It is with huge thanks to our generous live streaming supporters that we have been able to offer the live stream free of charge this year,” said NEF Chairman Tim Brigstocke. “NEF is a not-for-profit event organised by a committee including many volunteers. 

 

“Our intention is to share educational, important and topical information with as many members of the equestrian sector as possible, to support progress and cohesion within the sector. With this year’s free live stream, together with our discounted live event afternoon tickets for educational establishments, we will be able to achieve our intention with even greater effect.”

This year’s NEF programme will cover key issues shaping the future of equestrianism, that should be relevant for everyone in the equestrian sector—professionals, amateurs, and horse owners alike. Highlights include:

• The Equine Industry in a Changing World: A Parliamentary perspective on the sector’s current status and a review of the Paris 2024 Olympic Games.
• Equine Health Updates: The latest information on some of the most serious disease threats to horses in the UK.
• Equine Feeds: A focus on feed safety and legality, the vital role of forage, and sources for reliable nutrition advice.
• Equine-Assisted Services: An in-depth look at the roles horses play, both ridden and unmounted, in supporting people.
• The Memorial Lecture: Case studies exploring how charities are collaborating to address emerging equine welfare challenges in Britain.
• The Sir Colin Spedding Award: Announcement of this year’s recipient.
• Q&A Sessions: Opportunities for attendees and live stream viewers to engage directly with the discussions.
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To register for the Live stream visit https://NEF25LS.eventbrite.co.uk   

 

or to book a face-to-face, all-day ticket go to: https://NEF25.eventbrite.co.uk

 

Further information can be found on the NEF website.  

https://www.nationalequineforum.com/forum-2025/

Discovery links genes to performance-limiting disease in Thoroughbred racehorses

(c) Miltudog Dreamstime.com

 New research has identified specific genetic markers linked to Recurrent Laryngeal Neuropathy (RLN), a disease that significantly impacts the performance of Thoroughbred racehorses. This discovery, hailed as a major step forward in combating this debilitating condition, paves the way for the development of a genetic test to identify horses with a threefold increased risk of developing RLN. 

Often referred to as laryngeal hemiplegia or "roaring," RLN is an upper respiratory tract (URT) disorder that affects up to 18% of Thoroughbred horses. The condition is characterised by the progressive degeneration of the recurrent laryngeal nerve, which controls the muscles that open the horse’s airway. As the disease progresses, airflow during exercise becomes restricted, leading to laboured breathing, reduced oxygen intake, and impaired athletic performance.

 

RLN represents a significant challenge for the Thoroughbred racing industry due to its economic and competitive implications. While pre-purchase examinations, including upper respiratory endoscopy ("scoping"), can detect RLN, resting evaluations in young horses often fail to identify the disease or predict its future onset.

 

To tackle these challenges, researchers at University College Dublin, in collaboration with Equinome and a world-class Thoroughbred training facility, conducted an extensive study funded by Research Ireland. The research team employed state-of-the-art diagnostic methods, including resting and overground exercising endoscopy of the upper airway, as well as laryngeal ultrasonography. This rigorous approach ensured accurate phenotyping of horses as either RLN cases or controls.

 

The study analysed over 200 Thoroughbred horses in training, utilizing both clinical evaluations and genetic testing. The case-cohort group was supplemented with detailed questionnaires to capture additional phenotypic data. A full report of the research is published in the Equine Veterinary Journal.

 

Using advanced DNA technologies, researchers conducted a genome-wide association study (GWAS) to identify genetic variants associated with RLN. They genotyped 43,831 single-nucleotide polymorphisms (SNPs) from 235 horses (110 RLN cases and 125 controls) and estimated the heritability of the trait. The findings revealed a set of genetic markers that significantly contribute to RLN risk, independent of other factors such as height.

 

This discovery is particularly important because it confirms a genetic predisposition to RLN and identifies specific markers that could be used to predict the disease in Thoroughbreds.

This research marks a significant advance in equine genetics and respiratory health, offering new hope for addressing RLN, a disease that has long plagued the Thoroughbred racing industry. The ability to identify horses with a higher genetic risk for RLN has far-reaching implications for the Thoroughbred racing industry. 

 

The next step will involve translating these findings into a practical genetic test that can be readily adopted by breeders, trainers, and veterinarians.

 

UCD Professor in Equine Genomics and Chief Science Officer at Equinome, Emmeline Hill said the new findings would “lay the groundwork for the development of a genetic test to improve the welfare of horses that have a genetic predisposition to the disease. 

“As well as identifying horses with an increased risk of disease, this new information could also inform breeding guidance to reduce the incidence of the disease and provide targets for new therapies.”

Project lead Lisa Katz, UCD Professor in Equine Internal Medicine, added: “Understanding the genetic risk of your horse for roaring can help with early intervention and management. This might include monitoring highly predisposed horses more closely and considering surgical interventions at an earlier stage to improve treatment success.”

 

For more details, see: 

 

A genome-wide association study for recurrent laryngeal neuropathy in the Thoroughbred horse identifies a candidate gene that regulates myelin structure

Charlotte L. McGivney, Beatrice A. McGivney, Gabriella Farries, Katie F. Gough, Haige Han, Amy R. Holtby, David E. MacHugh, Lisa Michelle Katz, Emmeline W. Hill

Equine Vet J (2025)

https://doi.org/10.1111/evj.14461

Mediterranean donkey milk production

(c) Zoran Nikolic Dreamstime.com

 Donkey milk has been prized since ancient times for its cosmetic and nutritional benefits. According to legend, Cleopatra, famed for her beauty, bathed in donkey milk to maintain her radiant complexion. It is said that she kept a herd of 700 donkeys to ensure a steady supply of milk for her beauty rituals.

In modern times, donkey milk is increasingly recognised as a valuable dairy alternative due to its unique composition and health benefits. But is all donkey milk the same, or do breed differences influence its properties?

 

A study led by Mohamed Aroua, in collaboration with researchers from the University of Jendouba, Tunisia, and the University of Molise, Italy, examined the milk production and nutritional quality of two Mediterranean donkey breeds, Masri and North African. The research analysed the volume of milk produced and its nutritional components, including proteins, fats, amino acids, and fatty acids.

 

Nutritional analysis highlighted notable differences in milk composition:

 

• Protein Content: North African donkey milk had higher protein levels (1.45 g/100 g) and β-lactoglobulin, essential for nutritional and functional properties.

• Fat Content: Masri donkey milk contained more fat (1.16 g/100 g), particularly unsaturated fatty acids such as oleic acid, which are known for their cardiovascular benefits. In contrast, North African milk had higher levels of palmitic acid, a saturated fat.

• Amino Acids: North African milk was rich in glutamate, while Masri milk had higher levels of aspartate.

 

North African donkeys outperformed Masri donkeys in milk yield, producing significantly more milk over the lactation period. This makes them particularly suitable for functional food applications where higher yield and protein content are desired.

 

Both breeds demonstrated the potential to produce high-quality milk suitable for human consumption. However, North African donkeys showed an edge in terms of productivity and nutrient profiles, making their milk better suited for functional food and nutritional applications.

 

This research highlights the promise of donkey milk as a niche, health-focused dairy product. Promoting its production could support sustainable agricultural practices and enhance rural economies.

 

Promoting donkey milk production could support sustainable agricultural practices and contribute to rural economic development by introducing a niche, health-focused dairy product into the market.

 

For more details, see:

 

Aroua, Mohamed, Antonella Fatica, Samia Ben Said, Mokhtar Mahouachi, and Elisabetta Salimei. 

Preserving Mediterranean Donkeys: A Study on Milk Production and Nutritional Benefits

Animals (2024) vol 14, no. 24: 3713. 

https://doi.org/10.3390/ani14243713

Air sampling for flu detection

(c) Tnmkiley Dreamstime.com

 Air sampling may provide a safe and effective method for detecting horses infected with equine influenza virus (EIV), according to new research from Japan.

EIV, a highly contagious respiratory disease in horses, spreads through aerosolised droplets, direct contact, and contaminated surfaces (“fomites”). Traditionally, confirming EIV infection requires nasopharyngeal swabs, which can be invasive and challenging, especially for untrained or aggressive horses.

 

A study conducted by researchers at the Equine Research Institute, Japan Racing Association, in Shimotsuke, Tochigi, Japan, has demonstrated that EIV can be recovered directly from the air surrounding infected horses. The research, led by Manabu Nemoto and colleagues and published in Veterinary Microbiology, involved experiments with two horses intentionally infected with EIV and housed in individual stalls.

 

Air samples were collected daily for 13 days post-inoculation using an air sampler. The findings showed that EIV RNA was detected in 26 out of 28 air samples using real-time RT-PCR and in 23 samples using a rapid molecular test kit. Significantly, viral RNA was detected in the air before the horses displayed clinical symptoms, emphasising the potential of air sampling for early detection.

 

The research team highlighted that air sampling is a non-invasive and safe alternative to traditional methods, avoiding the risks associated with swab collection. Additionally, the combination of air sampling with rapid molecular diagnostic kits, which can identify viral RNA in under 30 minutes, offers a practical and efficient approach for monitoring and controlling EIV outbreaks.

 

They suggest that this method could be particularly beneficial in quarantine facilities and other high-risk settings where early detection and containment of EIV are essential.

 

For more details, see:

 

Manabu Nemoto, Nanako Kawanishi, Yoshinori Kambayashi, Hiroshi Bannai, Takashi Yamanaka, Koji Tsujimura,

Detection of equine influenza virus gene in the air around infected horses,

Veterinary Microbiology, (2025), Vol 302, 110388,

 

https://doi.org/10.1016/j.vetmic.2025.110388

Horses in Asia Found Infected with H5N1 Avian Influenza

(c) Nawrob Dreamstime.com

A recent study has revealed that horses in Asia have been infected with H5N1 avian influenza,
with these infections occurring undetected.  

The research, led by Professor Pablo Murcia from the MRC-University of Glasgow Centre for Virus Research, in collaboration with an international team of scientists from the US and Mongolia, involved antibody testing on horse herds in Mongolia.  The findings, published in Emerging Infectious Diseases, reveal asymptomatic infections in Mongolian horse herds.

 

The researchers tested horse herds in two distinct Mongolian regions: a wetland area with a high population of wild birds and a dry area with low bird density. The results showed higher exposure rates in the wetland region. Importantly, there were no reports of previous respiratory disease outbreaks among the horses, suggesting that the infections were acquired asymptomatically.

 

These findings confirm that avian influenza can spread to other species, including horses. While equine influenza is typically caused by the H3N8 subtype, the detection of H5N1 highlights the potential for avian influenza to infect horses.

The study raises concerns about cross-species transmission, particularly in agricultural environments where horses may be exposed to infected livestock. Since March 2023, the rapid spread of H5N1 in US dairy cattle has amplified the risk of horses contracting avian influenza.

Coinfection with H5N1 and equine influenza (H3N8) could result in genetic reassortment, potentially creating new influenza strains with unpredictable consequences for animals and humans. Professor Murcia noted parallels to the 2009 swine-origin influenza pandemic, emphasizing the importance of preventing such reassortment events.

The researchers conclude by recommending serologic surveys in premises that keep horses. Such studies, they say, would aid early virus detection, provide a comprehensive picture of the changing ecology of avian influenza viruses, and inform the design of control measures to prevent influenza emergence.

This study highlights the need for:

1. Enhanced surveillance of influenza infections in horses, particularly in regions with high wild bird densities or significant interaction with infected livestock.
2. Strengthened biosecurity measures to reduce interspecies transmission in agricultural settings.
3. Further research into the mechanisms of avian influenza spillover and the potential for new virus emergence.

For more details, see: 

 

Batchuluun Damdinjav, Savitha Raveendran, Laura Mojsiejczuk, Ulaankhuu Ankhanbaatar, Jiayun Yang, Jean-Remy Sadeyen, Munir Iqbal, Daniel R. Perez, Daniela S. Rajao, Andrew Park, Mafalda Viana, and Pablo R. Murcia (2025)

Evidence of Influenza A(H5N1) Spillover Infections in Horses, Mongolia.

Emerging Infectious Diseases, 31(1) 

https://doi.org/10.3201/eid3101.241266 

https://www.gla.ac.uk/news/headline_1134067_en.html

Survey on SGLT2 Inhibitor Use in Horses with EMS or PPID

(c) Brian Sedgbeer Dreamstime.com

Have you used an SGLT2 inhibitor (one of the          "-flozin" drugs) to treat your horse? If so, the Equine
Cushing's and Insulin Resistance Group (ECIR) invites you to contribute to an important research initiative.

Sodium-glucose cotransporter 2 inhibitors (SGLT2i), such as ertugliflozin and canagliflozin, are increasingly used to manage equine metabolic syndrome (EMS), particularly in horses with laminitis that has not responded to dietary changes. These drugs have shown potential benefits, including reducing serum insulin levels, aiding weight loss, and improving laminitis associated with hyperinsulinemia.

However, concerns have arisen about possible side effects, such as elevated serum triglycerides and liver enzyme levels, lethargy, and increased drinking and urination.

Dr. Kellon of the ECIR Group has created a survey to investigate factors that may influence the outcomes of SGLT2 inhibitor use in horses. This includes individual horse characteristics, comorbidities, and dietary factors that may contribute to or mitigate adverse effects.

If you are an owner, veterinarian, or caretaker of a horse receiving one of these drugs—such as canagliflozin, ertugliflozin, or dapagliflozin—you are encouraged to participate in the survey. Your insights will help enhance understanding and improve the management of metabolic disorders in horses and ponies.

The survey can be found here www.surveymonkey.com/r/YM5JD9G 

 

See also:

Eleanor M. Kellon, V.M.D. (Equine Nutritional Solutions) 

www.drkellon.com

 

Equine Cushing's and Insulin Resistance Group Inc.

www.ecirhorse.org

Green alternatives in equine reproduction

 The overreliance on plastic materials in all areas of modern life, including veterinary practice, poses a significant environmental challenge due to the pollution it generates.

Artificial insemination, a common technique in equine breeding programs, is a good example of the widespread nature of plastics in veterinary work. The procedure typically relies on disposable plastic items, such as insemination catheters and semen straws, which are essential for the collection, storage, and transfer of genetic material. However, their single-use nature contributes heavily to plastic waste. 

As part of the search for sustainable solutions, Noelia González and colleagues conducted a study to explore sustainable alternatives to conventional plastic semen straws. The study evaluated various biodegradable materials, including bamboo, avocado, grass, paper, Kraft paper, wheat, and rice, focusing on their suitability for preserving refrigerated, extended equine semen.

Among the materials tested, bamboo and avocado emerged as the most promising options. Bamboo displayed strong structural integrity, making it a durable and reliable container, However, avocado-based straws were particularly effective in maintaining sperm quality parameters, such as motility and movement kinetics, without introducing contaminants.

The research team conducted detailed assessments of the straws’ structural integrity and their ability to preserve semen quality after 24 and 96 hours of refrigeration. Both bamboo and avocado straws performed within acceptable ranges, but avocado straws yielded superior results. Additionally, microbiological control tests confirmed the absence of bacterial growth in both straw types, further supporting their potential as safe alternatives to plastic.

The findings suggest that avocado-based straws could serve as a viable alternative to plastic straws in artificial insemination procedures, offering an environmentally friendly solution without compromising the success of reproductive practices.

 

For more details, see:

 

González N, Peñalosa A, de Blas I, Gil L. 

Sustainable Alternatives to the Reduction of Plastic Straws Used with Chilled Equine Semen. 

Animals. (2024); 14(23):3388. 

https://doi.org/10.3390/ani14233388

Hand injuries more common during horse handling than riding

(c) Marina Sokalskaya Dreamstime.com

Horse-associated hand injuries occur more frequently during horse handling than riding according to a new study.

 The most common injuries in equestrian sports involve the head, followed by injuries to the upper extremities and the thoracic and lumbar spine. Among hand injuries, riding a horse ranks third as a cause after ball sports and cycling.

A study conducted in Northern Germany by Benedikt Ritter and colleagues at the Department of Plastic, Aesthetic, Hand, and Reconstructive Surgery at Hannover Medical School examined the circumstances, mechanisms, and locations of horse-related hand injuries, as well as the use of protective equipment. The work is published in the Archives of Orthopaedic and Trauma Surgery

This retrospective cohort study analysed records of patients admitted to the hand trauma centre. Complete records, including follow-up data, were available for 39 patients over a five-year period. The cohort included 35 females and 4 males, with ages ranging from 9 to 65 years. Only 7.7% of participants were professional riders, while 92.3% were amateur riders, some with equestrian training qualifications.

Data from clinical records and telephone interviews were analysed to investigate the mechanisms of trauma and injury patterns.

Key Findings:

• Over half of the injuries (21 cases) occurred while leading the horse, primarily due to traction forces exerted by bridles or lead ropes on the fingers.
• Falls accounted for 13 cases, and 5 cases resulted from bite injuries.
• The phalanges (fingers) were the most injured site (33 cases), followed by the metacarpal bones (hand) (4 cases) and the carpal bones (wrist) (2 cases).
• Fractures were present in over half (20) of cases.
• avulsion amputations occurred in nine (23.1%) of patients 
• Thirty one cases (79.5%) required surgical intervention.

The researchers note that, while horse-related injuries represent a small proportion of total emergency visits, they are disproportionately severe. They say that this emphasises the need for targeted preventive measures and specialised care to address the high rate of serious outcomes associated with these injuries.

They recommend wearing appropriate protective gloves to prevent hand injuries, as well as using self-opening panic hooks with overload protection to prevent excessive traction.

 

For more details, see: 

 

Ritter, B., Dastagir, N., Tamulevicius, M Bucher F, Obed D, Vogt PD, Dastagir K.

Equestrian-associated injuries of the hand: a retrospective analysis of injury mechanisms and patterns. 

Arch Orthop Trauma Surg (2024) 144, 4937–4945

https://doi.org/10.1007/s00402-024-05586-x

New tool to aid worm control

  

A free online tool to help horse owners evaluate the risk of worm infection has been launched. 

 

This simple, user-friendly resource, titled ‘What’s Your Worm Risk?’, has been developed by Austin Davis Biologics in collaboration with equine industry.

 

Anthelmintic resistance poses a significant threat to equine health and welfare, with cases now reported in all common horse worms. Effective worm control begins with assessing a horse’s risk of infection, providing essential information for decisions regarding management, testing, and treatment.

 

The tool uses widely accepted principles of equine worm control to classify each horse's risk of infection as low, moderate, or high, based on details provided by the owner. It also accounts for the potential impact of grazing companions, where applicable.

 

Jacqui Matthews, a specialist in parasitology and director of veterinary science at Austin Davis Biologics, explains: “The tool is designed to support horse owners in assessing their horse’s risk of infection, helping them make informed decisions about testing and treatment.”

 

To reduce the risk of wormer resistance, experts recommend combining excellent pasture management—reducing worm transmission from paddocks—with regular testing to guide treatment decisions.

• Faecal worm egg count (FEC) tests provide an insight into worm egg shedding levels in manure.
• Antibody tests reveal the horse’s exposure to worm infections.

 

This approach minimizes the need for blanket wormer treatments, which are known to promote resistance and reduce the effectiveness of essential drugs.

 

The ‘What’s Your Worm Risk?’ tool has been optimised for use on smartphones, laptops, and desktop computers and is tailored specifically to UK conditions.

 

By integrating testing and evidence-based treatments into worm control plans, horse owners can protect their animals while reducing the risk of drug resistance in the equine population.

 

For more details, see: 

 

https://www.whatsyourwormrisk.com

New reporting initiative for clinical redworm disease in the UK

 Equine Infectious Disease Surveillance (EIDS) has launched RedWatch, a new initiative designed for vets to report cases of redworm disease in horses.

 

Based at Cambridge University, EIDS collects and analyses national disease data from diagnostic laboratories and veterinary practices across the UK. Their work provides valuable insights into the prevalence of equine infectious diseases. In addition to operating various surveillance programs, EIDS offers disease control advice and shares critical disease information through platforms like the International Collating Centre (ICC), EquiFluNet, and the Equine Quarterly Disease Surveillance Report, a collaborative effort with BEVA, Defra, and APHA.

 

Historically, large redworm infections—most notably caused by Strongylus vulgaris—have been significantly reduced in the UK due to the widespread use of anthelmintics. However, the overuse of these treatments has led to growing resistance, especially in small redworms (cyathostomes). As a result, there has been a shift towards reducing anthelmintic use and focusing on management-based strategies to control parasitic diseases.

 

Concerns remain, however, that reduced anthelmintic use could unintentionally alter the patterns of parasite-associated diseases. To address this, EIDS has introduced RedWatch, a targeted surveillance initiative.

 

RedWatch will collect and disseminate case data on diseases caused by small and large strongyles, including cyathostominosis and Strongylus vulgaris. Veterinary surgeons are encouraged to submit information via an online form, recording:

·       Vet and practice details

·       Case-specific information

·       Diagnostic methods

·       Clinical signs observed

·       Data about the premises and equine population

·       Potential risk factors

All submitted data will be securely stored and anonymised for public reporting. This will support education, awareness, and ongoing research into equine parasitology.

 

Large strongyles are often only detected during post-mortem examinations (PME) and are likely to be captured mainly through the Equine Quarterly Disease Surveillance report’s post-mortem surveillance section.  However, RedWatch will allow veterinary surgeons to report large strongyle cases that have not undergone an official PME.

 

"RedWatch is an exciting step in equine parasitology surveillance," said Fleur Whitlock, veterinary surgeon and epidemiologist at EIDS. "This initiative relies on veterinary surgeons sharing data and their engagement is key to filling knowledge gaps. By contributing case reports, vets can directly support efforts to prevent these devastating diseases and help pave the way for new tools like real-time reporting and risk warnings.”

 

EIDS is generously funded by the UK’s Thoroughbred industry and is based at Cambridge University.

 

For more details, download the latest Equine Quarterly Disease Surveillance report

https://equinesurveillance.org/landing/resources/reports/dsr20243.pdf

 

Veterinary surgeons can record cases at

www.equinesurveillance.org/redwatch

Progress towards understanding the cause of Equine Grass Sickness

Pony with chronic grass sickness (McGorum et al)

 An international team of researchers has identified what they believe to be the probable cause of equine grass
sickness (EGS). Their findings suggest that a neurotoxin, similar in action to snake venom toxins but produced by pasture microbes, is the likely culprit. The work is set to be published in the Equine Veterinary Journal (EVJ) and is currently freely available online. A special editorial in the January 2025 issue of EVJ, authored by Bruce McGorum and colleagues, highlights the study’s findings and their implications. 

This breakthrough has the potential to pave the way for novel treatments and improved diagnostics for this devastating disease.

 

Equine grass sickness (EGS), also known as equine dysautonomia, is a major cause of mortality in horses and ponies in Great Britain, with more than 80% of cases proving fatal. First recognised in Scotland over 100 years ago, EGS remains most prevalent in Great Britain but has been reported in several northern European countries, South America, and very infrequently in North America.

 

EGS damages the autonomic nervous system, which controls involuntary bodily functions, with particularly severe effects on the gastrointestinal tract. Clinical signs range from depression, difficulty eating and swallowing, and weight loss to gastric reflux, abdominal pain, and death. The disease causes rapid degeneration of nerves, leading to paralysis of the gastrointestinal tract and other systemic effects such as muscle weakness, drooping eyelids, excessive salivation, sweating, and muscle tremors.

 

As there is currently no effective treatment for the most severe (acute and sub-acute) forms of the disease, horses are euthanised on humane grounds, typically within 24-48 hours of showing abnormal signs. In contrast, up to 50% of horses with the mild (chronic) form of grass sickness may survive with intensive nursing and supportive care.

Researchers from the Dick Vet Equine Hospital (RDSVS University of Edinburgh), Newcastle University, Istituto Zooprofilattico Sperimentale delle Venezie, and the University of Padova have made significant strides in identifying the neurotoxin responsible for EGS. Using electron microscopy, they examined post-mortem samples from horses with EGS and compared them to control samples. Their findings revealed that 72.2% of neuromuscular junctions (NMJs) in EGS-affected horses displayed abnormal morphology, compared to just 6.9% in controls.

 

These abnormalities are believed to represent a toxin-specific signature for a neurotoxic enzyme known as phospholipase A2. This enzyme disrupts the microscopic sites of communication between nerves and muscles (NMJs), which are crucial for normal muscle function.

 

Ongoing work aims to definitively identify the source of this toxin. Researchers suspect it is produced by a microbe, such as a bacterium or fungus, that thrives on pasture during the cold and dry weather conditions that typically precede outbreaks of EGS.

 

Interestingly, neurotoxic phospholipase A2 enzymes are also found in the venom of many poisonous snakes. While venomous snakes are not implicated in EGS, researchers hope that drugs being developed to treat nerve damage in snakebite victims could help promote nerve regeneration and recovery in horses with grass sickness.

 

Professor Bruce McGorum, R(D)SVS said: “Identifying a probable cause of Equine Grass Sickness represents a significant breakthrough. We hope that this discovery will lead to novel treatments and improved diagnostics for this devastating condition. We are very grateful for the generous support we have received from horse owners, veterinary surgeons, scientists, charities and funding bodies.” 

 

“Further work is underway to determine the source of this neurotoxin; it is likely to be produced by a microbe such as a bacterium or fungus which grows on the horse’s pasture during the cold and dry weather which precedes the disease.” 

 

This discovery represents a significant step forward in understanding equine grass sickness. By pinpointing the probable cause, researchers can now focus on developing effective treatments and preventive strategies. Advances in identifying the toxin’s source and exploring therapeutic interventions for nerve regeneration offer hope for reducing the impact of this devastating disease.

 

For more details, see:

 

McGorum, B., Pirie, R.S., Bano, L., Davey, T., Harris, J. and Montecucco, C. (2025), 

Neurotoxic phospholipase A₂: A proposed cause of equine grass sickness and other animal dysautonomias (multiple system neuropathies). 

Equine Vet J, 57: 11-18.

https://doi.org/10.1111/evj.14442

 

McGorum BC, Davey T, Dosi MCM, Keen JA, Morrison LR, Pirie RS, Shaw DJ, Harris JB.  

Equine grass sickness is associated with major abnormalities in the ultrastructure of skeletal neuromuscular junctions. 

Equine Vet J.  2025; 57(1): 193–202.

https://doi.org/10.1111/evj.14063