Dr Daniel W Carter and Dr J Ben Renfroe have patented a technique using botulinum toxin to reduce the tension in the deep digital flexor tendon of horses with laminitis.
Increased tension is one of the factors thought to contribute to rotation of the pedal bone. So relieving the tension may limit the deleterious changes in the foot.
The technique involves injecting a diluted solution of Botox (Botulinum toxin type A) into the deep digital flexor tendon in several places. The toxin blocks the release of the neuro- transmitter (acetylcholine) from the nerve endings. This temporarily prevents the muscle contracting.
Read more about it here